The top 10 significantly enriched KEGG pathways included Pathways in cancer, MAPK signaling pathway, PI3K-Akt signaling pathway, Proteoglycans in cancer, Prostate cancer, Lipid and atherosclerosis, Ras signaling pathway, Endocrine resistance, Chemical carcinogenesis -receptor activation and reactive oxygen species. This evidence concerns the gene AKT1 and Familial prostate cancer.