AFP and adrenal cortex carcinoma: An ACC is a rare malignancy that can affect any age group. Routine screening for LFS patients includes ultrasound examinations of the abdomen and pelvis every three months, complete urinalysis every three months, and blood tests every three months for beta-human chorionic gonadotropin (b-HCG), alpha-fetoprotein (AFP), 17-hydroxyprogesterone (17-OH-progesterone), testosterone, dehydroepiandrosterone sulfate (DHEAS), and androstenedione.