Finally, after adjusting for age and gender, increasing age was associated with an increased likelihood of exhibiting IPF (p=0.026, OR=1.289 [95%CI: 1.031-1.611]), whereas increased SIRT1 in "no serum supernatant" levels was associated with a reduction in the likelihood of IPF (p=0.014, OR=0.124 [95%CI: 0.023-0.653]) (Figure 2). Here, SIRT1 is linked to idiopathic pulmonary fibrosis.