In children with respiratory syncytial virus (RSV), increased ANGII, as a consequence of ACE2 disruption, was observed [26,32], thus, Gu et al. [33] exploited this finding to manage the infected mouse model of acute respiratory distress syndrome (ARDS) with recombinant ACE2, yielding promising cytoprotective effect against ALI. Here, ACE2 is linked to acute respiratory distress syndrome.