PUS1 and breast cancer: For a deeper exploration of PUS1’s predictive role in breast cancer, we conducted univariate and multivariate analyses on our cohort, and found the overall survival of patients was independently influenced by the PUS1 score (Univariate Cox P <0.0001, HR=5.176, 95% CI =2.420-11.07; Multivariate Cox P = 0.001, HR = 5.291, 95% CI =1.893-14.78) (Table 2).