Thus, to reduce unnecessary prostate biopsies for tumor malignancy prediction, radiomics signatures provide a more objective and independent prediction scheme.Prior study found that the detection rate of distant metastasis for 18F-PSMA PET/CT was higher between the PSA ≥ 30ng/mL and PSA ≥ 20ng/mL cohorts. The gene discussed is KLK3; the disease is neoplasm.