ADGRD1 and pancreatic adenocarcinoma: As shown in Figure 3(a), ADGRD1 expression was positively associated with TMB in ACC (P = 0.019), LGG (P = 0.001) and thymoma (THYM, P = 0.038), while negatively related to TMB in BLAC (P = 0.048), BRCA (P < 0.001), COAD (P = 0.019), KIRC (P = 0.025), KIRP (P = 0.016), LIHC (P = 0.029), LUAD (P < 0.001), LUSC (P = 0.012), pancreatic adenocarcinoma (PAAD, P < 0.001), PRAD (P = 0.007), SKCM (P = 0.010), STAD (P < 0.001), and UCEC (P < 0.001).