The results showed that ADGRD1 played an important role in the prognosis of twelve cancers, which included adrenocortical carcinoma (ACC), COAD, KIRP, LAML, brain lower grade glioma (LGG), liver hepatocellular carcinoma (LIHC), LUAD, LUSC, mesothelioma (MESO), READ, sarcoma (SARC), and STAD. The gene discussed is ADGRD1; the disease is cancer.