According to KEGG pathway analysis, the most enriched pathways of ADGRD1 and associated immune-related genes in NSCLC were “cytokine−cytokine receptor interaction,” “hematopoietic cell lineage,” and “phagosome.” The findings imply that these genes possibly have critical effects on NSCLC cancer pathogenesis, progression, and tumor therapy through revealing tumor molecular life processes via these pathways. The gene discussed is ADGRD1; the disease is neoplasm.