The likenesses between COVID-19 and STING-associated vasculopathy with onset in infancy (SAVI) syndrome suggest that postponed STING over induction, once the self-DNA injury happens in contaminated cells, causes a harmful additional of IFN release and/or NF-κB stimulation and brings about the most severe condition of the COVID-19 symptoms [68]. Here, STING1 is linked to STING-associated vasculopathy with onset in infancy.