Proteinuria, creatinine increased, renal failure, alanine aminotransferase increased, aspartate aminotransferase increased, abdominal pain, constipation, diarrhea, nausea, vomit, stomatitis, dysphonia, dyspnea, anemia, leukopenia, thrombocytopenia, neutropenia, hypertension. This evidence concerns the gene GPT and anemia.