Previous studies found that miR‐451 inhibited the PI3K/AKT/Snail signalling pathway by activating calcium binding protein 39 in GBM, thereby inhibiting EMT and metastasis,37 and miR‐200b‐3p promoted E‐cadherin expression by down‐regulating ERK5, resulting in reduced invasion ability of GBM cells.38 This evidence concerns the gene AKT1 and glioblastoma.