Latorre et al. [25] found that the rates of CD27− and CCR4+ in IFN-γ+ TNF-α+CD4+ T cells stimulated by ESAT−6/CFP−10 or PPD had a high diagnostic value and a high diagnostic accuracy between ATB and LTBI, but the ATB and LTBI participants in the study were enrolled within the first 4 weeks of initiation of anti-TB therapy or prophylactic anti-TB therapy, and it is questionable whether anti-TB therapy interfered with the results. The gene discussed is CD4; the disease is tuberculosis.