The study underlined that LINC02418 acted as a tumor driver by negatively regulating cell apoptosis through the miR-34b-5p/Bcl-2 axis, indicating that the LINC02418/miR-34b-5p/Bcl-2 axis was one potential indicator for prognosis prediction and a promising therapeutic target for CRC treatment (Fig. 1A) [16]. This evidence concerns the gene BCL2 and colorectal carcinoma.