Further Logistic regression analysis showed that c–Rel and p65 are related to early infection of HPV16, their nuclear expressions are positively correlated with the occurence of early HPV16 infection with statistically significant (OR = 4.282, 8.214; 95% confidence interval: 1.303–14.078, 1.980–42.696; P < 0.05); while c–Rel and p50 are related to late infection of HPV16, their nuclear expressions are positively correlated with the development of HPV16 infection with statistically significant (OR = 2.449, 3.978; 95% confidence interval: 1.154–5.197, 1.595–9.924; P < 0.05) (Table 3). This evidence concerns the gene NFKB1 and infection.