The real-time qPCR results showed that DRD3 mRNA expression in HCC tissues was lower than that in adjacent nontumor tissues and that DRD3 mRNA expression was higher in the noncancerous cell line Miha than in HCC cell lines, suggesting that DRD3 may be a potential antitumor therapeutic target in HCC. Here, DRD3 is linked to hepatocellular carcinoma.