Aerobic exercise can also modulate the inflammatory/anti-inflammatory and oxidative/antioxidative balance in the early stage of LPS-induced lung injury, which leads to a decrease in the release of inflammatory mediators such as TNF-α, IL-6, IL-10, IL-1β, IL-17, GM-CSF, and CXCL1/KC [17, 19]. This evidence concerns the gene IL10 and injury.