Aseervatham et al. reported that Matrix Metalloproteinase 20 (MMP20) played a tumorigenic role on Oral Squamous Cell Carcinomas (OSCCs) by upregulating the genes related to invasion, metastasis, angiogenesis, and epithelial-mesenchymal transition (EMT)24. This evidence concerns the gene MMP20 and oral cavity squamous cell carcinoma.