The increased in CD8 T cell infiltration into tumors (Fig. 1C), in cytotoxic and T cell gene signatures, as well as the prevalence of dendritic cell gene signature in h PD-L1+ MC38 tumors (Fig. 2E) suggested that cytotoxic CD8 T cells were the main immune cell population responsible for the anti-tumor activity of KD033 in PD-L1+ tumors. The gene discussed is CD8A; the disease is neoplasm.