CXCR2 and pancreatic neoplasm: In addition, we also noticed elevated levels of several CXCR2 ligand‐encoding genes, including Cxcl1, Cxcl3 and Cxcl5, in Neu‐Setd2KO cells compared with Neu‐Setd2WT cells, indicating that neutrophils reprogrammed by Setd2‐deficient pancreatic tumor cells could further strengthen the recruitment of neutrophils (Table S1, Supporting Information).