CD274 and neoplasm: In addition to tumor cell‐derived PD‐L1, immunosuppressive neutrophils with elevated PD‐L1 levels participate in the inhibition of cytotoxic CD8+ T cells.[7, 14] As shown in Figure 3I, neutrophils treated with Setd2KO cell‐conditioned medium displayed higher PD‐L1 levels than those treated with Setd2WT cell‐conditioned medium (Figure 3I).