CSF2 and pancreatic neoplasm: Consistent with previous reports, we demonstrated that knockdown of Cxadr could facilitate AKT activation and E‐cadherin downregulation in pancreatic tumor cells (Figure 6A).[8a] In addition, the mRNA levels of both Cxcl1 and Csf2 were also upregulated in step with AKT phosphorylation (Figure 6A).