Our previous study determined the role of SETD2 in pancreatic tumorigenesis, in which SETD2 deficiency promotes acinar‐to‐ductal metaplasia and EMT‐related metastasis.[8a] Interestingly, we found that pancreatic tumor cells lacking Setd2 (KPC1199‐Setd2KO, hereafter termed Setd2KO) grew slightly slower than control cells (Setd2WT) in vitro (Figure S1A, Supporting Information). The gene discussed is SETD2; the disease is pancreatic neoplasm.