To further examine whether Neu‐Setd2KO (Setd2KO tumor‐primed neutrophils) had direct effects on CD8+ T cells, we set up a coculture system in which CD8+ T cells from the spleen were cocultured with or without neutrophils (sorted from bone marrow) upon treatment with conditioned medium from Setd2WT and Setd2KO cells, respectively (Figure 3E). The gene discussed is CD8A; the disease is neoplasm.