CG1 was upregulated in kidneys of patients with CKD and approximately 80% of KIM-1+ tubules expressed CG1 (Figure 1, A and B, and Supplemental Figure 1, A and B; supplemental material available online with this article; https://doi.org/10.1172/JCI158096DS1). The gene discussed is HAVCR1; the disease is chronic kidney disease.