Some of these tumours were associated with amplification or overexpression of CCNE1, as we characterized it in MPM_31 and MPM_34 cell lines; and/or with high transcript levels of E2F1, or E2F3 in the peculiar M631PT patient in Bueno's cohort (Fig. 7A; Table S9). The gene discussed is E2F3; the disease is neoplasm.