These antigen-specific CXCR5+ CD8+ T cells exhibit memory-like properties and are co-expressed with antigen-specific T cell factor 1 (TCF1+) CD8+ T cells in the germinal center during lymphocytic choriomeningitis virus (LCMV) Cl13 infection (He et al., 2016; Im et al., 2016). Here, CXCR5 is linked to infection.