CD4 and cancer: B cells (P < 0.001), T cells CD4+ naïve (P = 0.004), T cells CD8+ naïve (P = 0.031), T cells CD8+ (P = 0.015), cancer-associated fibroblasts (P < 0.001), neutrophils (P = 0.001), and B cells plasma (P = 0.001) were decreased in the high-risk group (Figure 7F).