KRT5 and neoplasm: So far, there is no research report on the construction of TNBC prediction model based on the HSPA8 expression, so we conducted a multi-Cox regression analysis by integrating various clinical parameters from the experimental data, which showed that TNBC tumor stage, lymph node metastasis, CK5/6 expression, and HSPA8 expression were independent prognostic factors, and further created a nomogram to forecast the death risk of individual sufferers and help optimize treatment decisions.