By comparing tumor and normal liver tissue, we found that genes enriched in the following functional categories, including myeloid dendritic cells, memory B cells, CD4+ T cells, Tregs, T-cell follicular helper, neutrophils, M0 and M2 macrophages, resting/activated NKs, and resting mast cells were differentially expressed between the high- and low-risk groups. The gene discussed is CD4; the disease is neoplasm.