Searching in ClinicalTrials.gov, we found some clinical trials on OVs (e.g., Seneca Valley virus, recombinant vaccinia GM-CSF, reovirus, herpes simplex virus, oncolytic measles virus, oncolytic adenovirus, and Newcastle virus) were combined with chemotherapy or ICIs in solid tumor treatment (e.g., pancreatic cancer, lung cancer, glioblastoma, brain cancer, and advanced bladder carcinoma) are in recruitment. The gene discussed is PPP1R3A; the disease is pancreatic neoplasm.