Moreover, high expression of PEG3 was positively associated with poor prognosis of Asian HCC patients rather than non-Asian patients (Figure 5C-D, S10C, all cutoff points were defined by surv_cutpoint function of R survminer package), which also suggests PEG3 as a biomarker in Asian HCC. This evidence concerns the gene PEG3 and hepatocellular carcinoma.