On the other hand, co-delivered CD47 antibody blocked the tumor "don't eat me" signal, synergistically enhancing the phagocytosis efficiency of CAR-M on GSCs, and facilitating its antigen presentation of CAR-M to activate the specific T cell immune response, which cleared the residual GSCs after surgery, formed immune memory, and avoided GBM recurrence. This evidence concerns the gene CD47 and glioblastoma.