We contrast this model with that of the murine neu deletion (NDL) HER2+ mammary adenocarcinoma model, which is composed of a dense tumor network (tumor cellularity >80%) with a greater fraction of lymphocytes, natural killer (NK) cells and plasmacytoid dendritic cells (pDCs) surrounded by fat cells 33. This evidence concerns the gene ERBB2 and breast adenocarcinoma.