For deciphering the precise influence of tumor-associated macrophages (TAM) after X-body treatment, cells with high transcript of CD11b (ITGAM), F4/80 (ADGRE1) and CD115 (Csf1r) were defined as macrophages which accounted for nearly half of the tumor-infiltrating immune cells. The gene discussed is ADGRE1; the disease is neoplasm.