CRP concertation has a history of being associated with the severity of viral infections such as H1N1 influenza pneumonia (7), and has been pointed out early-on as a severity indicator of COVID-19 as shown in a systemic review by Ikeagwulonu et al (8) which included 61 studies with a total of 13891 COVID-19 patients, demonstrating that severe cases had constantly higher levels of CRP compared to mild cases, and that the increase in C-reactive protein was statistically significant in 78.7% of the cases included. The gene discussed is CRP; the disease is viral infectious disease.