KRAS and endometriosis: EnOC is associated with endometriosis and has a genetic resemblance to the endometrial tissue.112 They account for about 10–20% of all OCs diagnosed at the early stage and are sensitive to platinum-based chemotherapy.77 They are further classified as high- and low-grade endometrioid carcinoma, in which the high-grade closely resembles HGSOC clinically and molecularly.77,112 The genes that are frequently mutated areCTNNB1 ~50%,PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit α) ~40%,PTEN ~25%,KRAS ~35%, andARID1A (AT-rich interaction domain 1A) ~30%.