In AF patients on phenprocoumon, increasing TTR was associated with significantly decreased risk of all-cause (IRR 0.35, 95%CI 0.14–0.87, p = 0.025), but not bleeding-related hospitalisation (IRR 0.13, 95%CI 0.01–1.38, p = 0.09). Here, TTR is linked to atrial fibrillation.