After combining different plasma proteins, we showed that the combination of ECM1, CLEC3B, IP10 and SELL generated the best AUC to discriminate (1) ATB from HD groups (95% sensitivity and 92% specificity), and (2) fast vs slow sputum culture converters at baseline (83%sensitivity and of 84% specificity). Here, CXCL10 is linked to Huntington disease.