We also note that in breast cancer research, the high expression of HOTAIR is closely related to breast cancer lymph node metastasis (LNM), and there is a direct strong correlation with the expression of androgen receptor (AR) These data confirm that HOTAIR is involved in the regulation of AR pathway, which provides the possibility for AR-positive TNBC patients to establish new treatment strategies34. Here, HOTAIR is linked to breast carcinoma.