CTLA4 and psoriasis: Moreover, we observed higher CTLA-4 and TIGIT expression by Foxp3int Tregs of PsA patients as compared to psoriasis patients (CTLA-4 + Tregs: 2.3% vs. 3.3%, P= 0.040)(TIGIT + Tregs: 63.2% vs. 69.1%, P = 0.017)(Fig. 4A and B).