Higher levels of tenascin‐C (TNC) and fibrinogen‐β in plasma EVs of COVID‐19 patients may trigger proinflammatory cytokines via the nuclear factor‐κB (NF‐κB) pathway, leading to increased levels of TNF‐α, IL‐6, and C‐C motif chemokine ligand 5 (CCL5) (Sur et al., 2021). The gene discussed is CCL5; the disease is COVID-19.