Higher levels of tenascin‐C (TNC) and fibrinogen‐β in plasma EVs of COVID‐19 patients may trigger proinflammatory cytokines via the nuclear factor‐κB (NF‐κB) pathway, leading to increased levels of TNF‐α, IL‐6, and C‐C motif chemokine ligand 5 (CCL5) (Sur et al., 2021). Here, NFKB1 is linked to COVID-19.