The effect of CRP SNPs such as rs1800947, rs1417938, rs1130864, and rs3093077 on circulating protein level and the outcome has been assessed in a cohort of in-patients with cardiovascular diseases (e.g., IS) by Schulz et al. They found that both CRP level ≥5 mg/L and SNP rs1800947 of the CRP gene were independent risk factors for further adverse vascular events among patients with cardiovascular diseases within a 3-year follow-up [50]. The gene discussed is CRP; the disease is cardiovascular disorder.