In this case, NCCAH presented in a patient with <i>CYP21A2</i> and <i>CYP11B1</i> heterozygous mutations, one of which is a variant of unknown significance in <i>CYP11B1</i>.<h4>Case report</h4>A 30-year-old woman presented with a chief complaint of irregular menses and hirsutism. This evidence concerns the gene CYP21A2 and Hirsutism.