S100 calcium-binding protein P (S100P) for pancreatic cancer [39], synuclein gamma (SNCG) for breast and ovarian cancer [38], melanoma-related gene (MAG, E) [40], and dipeptidyl peptidase 6 for dipeptidyl peptidase 6 (DPP6) in melanoma are well-studied examples of hypomethylated genes in cancer [41]. The gene discussed is SNCG; the disease is familial pancreatic carcinoma.