PSMB5 and fragile X-associated tremor/ataxia syndrome: Toxicity related to elevated mRNA levels has already been shown to be a crucial mechanism of many other disorders related to the premutation state, including FXTAS, fragile X‐associated primary ovarian insufficiency (FXPOI; OMIM 311360), and fragile X‐ associated neuropsychiatric disorders (FXAND).23