Considering that SARS-CoV-2-induced inflammation [57], coagulopathies [58], and respiratory distress syndrome (ARDS) [59] are major causes of mortality in COVID-19 patients [60, 61], the known protective role of HMOX-1 activation regarding inflammation, inflammation-induced coagulation, lung damage, and ARDS [62–66] might suggest that the herbs and compounds we identified may act in diverse contexts. Here, HMOX1 is linked to newborn respiratory distress syndrome.