In the TCGA cohort, immature dendritic cells (iDCs), B-cells, activated dendritic cells (aDCs), neutrophils, mast_cells, tumor-infiltrating lymphocytes (TIL), human leukocyte antigen (HLA), T cell co-inhibition, Type_II interferons(IFN) response were infiltrated at high levels in a low-risk cohort, but MHC_class_I and Parainflammation decreased significantly (Fig. 4C, D). This evidence concerns the gene IFNA1 and neoplasm.