Age (p = 0.336), gender (p = 0.656), extra-nasal disease (p = 0.969), ≥ 2 comorbidities (p = 0.829), high β2-MG (p = 0.458), high LDH (p = 0.357), leukocytosis (p = 0.226), neutropenia (p = 0.619), monocytosis (p = 0.419), hypogammaglobulinemia (p = 0.353), high-risk PINK-E index (p = 0.864), tumor site infection (p = 0.925), tumor necrosis ≥ 50% (p = 0.834), CD30 expression (p = 0.728) and bulky disease (p = 0.080) were not predictive of OS. The gene discussed is TNFRSF8; the disease is neoplasm.