TGFB1 and hepatocellular carcinoma: Drug targets involving metastasis including SRC, PLOD2 and P4HA2 were also detected in all the HCC nine cell lines, while MMP14 only showed low expression in HepG2 and HepG2.2.15, and TGFB1 showed highest expression in HCCLM3 (Fig. 4e).