Further, we explore the clinical relevance of our finding in the Breast Cancer (Yau 2010) database where ER, PR, and HER2 negative basal-like breast cancer or TNBC selectively displays a positive correlation between EZH2 and KRT14 expression and H3K27me3 and KRT14 expression are found to be significantly upregulated in human TNBC metastasis as compared to their respective primary tumors. The gene discussed is PGR; the disease is breast carcinoma.