TGFB1 and fibromyalgia: Although RNA-seq showed that TRPV1 was the most highly upregulated gene after J2H-1702 treatment of TGF-β1-induced LX2 cells, we saw no significant change in the expression of TRPV1 and ADRA1A, both of which are fibromyalgia-related genes, following J2H-1702 treatment in TGF-β1-treated LX2 cells (Fig. 3E).