In order to detail the role of SULT1A1, we then made use of various cell models including HCT116 colorectal cancer cells proficient and deficient for p53 as well as V79 hamster fibroblasts and V79 cells genetically engineered for CYP1A2 and SULT1A1 expression (V79 CS). Here, SULT1A1 is linked to colorectal cancer.