TH and hypothyroidism: Overt hypothyroidism has been consistently associated with a higher risk of pregnancy complications, and impaired neurocognitive development of the conceptus.8, 12, 13Normal TH levels are essential for neuronal migration, myelination, and proper brain formation of the fetal brain.8, 14, 15Complications more commonly associated with overt hypothyroidism are:8, 11, 13, 16