The approaches tested to treat sexual dysfunction were as follows: lubricants and moisturizers (18 studies); phytoestrogens (14 studies); dehydroepiandrosterone (DHEA; 8 studies); ospemifene (5 studies); vaginal testosterone (4 studies); pelvic floor muscle exercises (2 studies); oxytocin (2 studies); vaginal CO2laser (2 studies); lidocaine (1 study); and vitamin E vaginal suppository (1 study). The gene discussed is OXT; the disease is sexual dysfunction.