The final prediction model derived from the RF algorithm for clinical outcome selected through the SHAP method included nine features: age, National Institutes of Health Stroke Scale (NIHSS) score, collateral status, and postoperative laboratory indices (albumin-to-globulin ratio (AGR), albumin, estimated glomerular filtration rate (eGFR), blood neutrophil count, C-reactive protein (CRP), and serum glucose level). The gene discussed is CRP; the disease is Stroke.